drugset / Trial / NCT00450879

Pazopanib in Treating Patients With Newly Diagnosed or Locally and/or Regionally Recurrent Breast Cancer That Can Be Removed By Surgery

NCT00450879

Phase 1 Terminated 19 enrolled National Cancer Institute (NCI)
NaSingle-groupOpen-labelTreatment

Summary

This pilot clinical trial studies how well pazopanib hydrochloride works in treating patients with breast cancer that is newly diagnosed or has come back at or near the same place as the original tumor and can be removed by surgery. Pazopanib hydrochloride may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by preventing the growth of new blood vessels necessary for tumor growth. Giving pazopanib hydrochloride before surgery may make the tumor smaller and reduce the amount of tissue that needs to be removed.

Timeline

Start
2007-01
Primary completion
2010-11
Completion
2011-09

Drugs

EvaluationDrugModalityDoseRoute
Subject Pazopanib Small molecule Oral

Indications