drugset / Trial / NCT00452218

Sorafenib Study: Dosing in Patients With Pulmonary Arterial Hypertension (PAH)

NCT00452218 ↗

Phase 1 Completed 12 enrolled University of Chicago Bayer · collab
Non-randomizedSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to assess the safety and tolerability of sorafenib in patients with PAH already on existing therapy with a prostacyclin \[epoprostenol (Flolan)\], treprostinil (Remodulin), or iloprost alone, or with or without sildenafil (Viagra/Revatio).

Timeline

Start
2007-03
Primary completion
2012-05
Completion
2012-05

Drugs

EvaluationDrugModalityDoseRoute
Subject Sorafenib Small molecule 400 mg —