The ELDORADO (Eligard®, Docetaxel and Radiotherapy) Study

Summary

The purpose of this study is to see if sequence inversion of Intensity - modulated Radiotherapy (IMRT) for prostate cancer, can improve the safety and deliverability of concurrent docetaxel chemotherapy with long - term hormonal therapy. The hypothesis is that inverting the traditional sequence of radiotherapy can delay the time to treatment - induced bowel toxicity.

Timeline

Start

2007-05

Primary completion

2017-02

Completion

2017-02

Publications

• Wilke D, Wood L, Cwajna S, Rutledge R, Hollenhorst H, Bowes D, Patil N, Ago CT, Pignol JP. Sequence Inversion to Facilitate Concurrent Radiotherapy and Systemic Therapy. A Proof of Principle Study in the Setting of a Phase II Randomized Trial in Prostate Cancer. Front Oncol. 2020 Sep 30;10:570660. doi: 10.3389/fonc.2020.570660. eCollection 2020.

Drugs

Indications