drugset / Trial / NCT00454298
Study Evaluating AGG-523 in Subjects With Severe Osteoarthritis Requiring Total Knee Replacement
RandomizedParallel-groupDouble-blindTreatment
Summary
The main purpose of the study is to find out if, after 4 weeks of dosing, signs of the investigational drug AGG-523, or its effects, can be measured in urine, blood, or the knee joint. A secondary purpose is to evaluate the safety of taking the drug either once a day or twice a day for 4 weeks.
Timeline
- Start
- 2007-05
- Primary completion
- 2008-03
- Completion
- 2008-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | AGG-523 | Small molecule | 900 mg | Oral |
| Comparator | AGG-523 | Small molecule | 1800 mg | Oral |