drugset / Trial / NCT00457392
A Study In Patients With Non-Small Cell Lung Cancer To Test If Erlotinib Plus SU011248 Is Better Than Erlotinib Alone
RandomizedParallel-groupTriple-blindTreatment
Summary
This study will test whether treatment with erlotinib plus SU011248 is better than erlotinib alone in patients with advanced/metastatic lung cancer who have received previous treatment with a platinum-based regimen.
Timeline
- Start
- 2007-07
- Primary completion
- 2010-07
- Completion
- 2012-12
Outcome
Missed primary endpoint
registry analysis (superiority or other test); Sunitinib + Erlotinib vs Erlotinib; p = 0.1933; Hazard Ratio (HR) 0.942 (95% CI 0.822 to 1.079); Log Rank NCT00457392 ↗
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Sunitinib | Small molecule | 37.5 mg | Oral |
| Comparator | Erlotinib | Small molecule | 150 mg | — |