Talotrexin in Treating Young Patients With Recurrent Solid Tumors or Leukemia That is Recurrent or Does Not Respond to Treatment

Summary

RATIONALE: Drugs used in chemotherapy, such as talotrexin, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. PURPOSE: This phase I trial is studying the side effects and best dose of talotrexin in treating young patients with recurrent solid tumors or leukemia that is recurrent or does not respond to treatment.

Timeline

Start

2007-02

Primary completion

2008-07

Completion

—

Outcome

Outcome not reported

Stopped: “Study withdrawn because of toxicity reported on the adult phase 1 trial.”

Drugs

Indications