A Pharmacokinetic Study of Dexmedetomine in Infants

Phase 1 Completed 36 enrolled Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

RandomizedParallel-groupSingle-blindTreatment

Summary

Blind randomized trial of a single bolus dose of dexmedetomine followed by a continuous infusion (CIVI) for up to 24 hours in infants who immediately post-operative from cardiac surgery and require tracheal intubation with mechanical ventilation in the post-operative period. Three bolus and infusion dose will be administered to a total of 36 patients.

Timeline

Start: 2004-05
Primary completion: —
Completion: 2006-11

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Dexmedetomine	Unknown	—	—

Indications

No indication recorded.