drugset / Trial / NCT00460278

Study of XL418 in Adults With Solid Tumors

NCT00460278 ↗

Phase 1 Suspended 63 enrolled Exelixis
Non-randomizedSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to evaluate the safety and tolerability of XL418 in subjects with solid tumors. XL418 is a new chemical entity that inhibits a spectrum of targets, including Akt and p70S6K, that mediate PI3 Kinase / PTEN signaling.

Timeline

Start
2007-04
Primary completion
—
Completion
—

Outcome

Outcome not reported

Stopped (Enrollment): “Enrollment suspended due to low drug exposure.”

Drugs

EvaluationDrugModalityDoseRoute
Subject XL418 Small molecule — Oral

Indications