drugset / Trial / NCT00461110

A Study of BMS-663513 in Combination With Chemoradiation in Subjects With Non Small Cell Lung Carcinoma (NSCLC)

NCT00461110

Phase 1 Terminated 35 enrolled Bristol-Myers Squibb
Non-randomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study is to determine the maximum tolerated dose and assess the safety and tolerability of escalating doses of BMS-663513 when given in combination with either radiotherapy alone or radiotherapy plus paclitaxel and carboplatin.

Timeline

Start
2008-01
Primary completion
2009-04
Completion
2009-04

Drugs

EvaluationDrugModalityDoseRoute
Subject Urelumab Monoclonal antibody 0.3 mg/kg Intravenous
Subject Urelumab Monoclonal antibody 1 mg/kg Intravenous
Subject Urelumab Monoclonal antibody 3 mg/kg Intravenous
Subject Urelumab Monoclonal antibody 6 mg/kg Intravenous
Subject Urelumab Monoclonal antibody 10 mg/kg Intravenous