drugset / Trial / NCT00462072
Centocor Microarray Study of Patients
NaSingle-groupOpen-labelTreatment
Summary
Specific Aim 1. To determine the transcriptome of peripheral blood mononuclear cells isolated monocytes and target tissues in IMIDs. Specific Aim 2. To analyze the change in gene expression profiles in patients with Crohn's disease, psoriatic and rheumatoid arthritis before and after infliximab therapy.
Timeline
- Start
- 2007-03
- Primary completion
- 2010-06
- Completion
- 2010-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Infliximab | Monoclonal antibody | 5 mg/kg | — |
| Background | Methotrexate | Small molecule | 12.5 mg | — |
| Background | Methotrexate | Small molecule | 20 mg | — |