Effect of Namenda on Short Term Memory and Attention in Patients With Mild to Moderate Traumatic Brain Injury
Summary
The purpose of this study is to determine whether memantine (Namenda) improves memory and attention in patients with mild to moderate traumatic brain injury.
Timeline
- Start
- 2007-04
- Primary completion
- 2010-12
- Completion
- 2010-12
Outcome
Missed primary endpoint
Stopped: “The study was stopped due to a lack of additional subjects.”
registry analysis (superiority or other test); Memantine vs Placebo; p = 0.55; Sign test; note: 6 week comparison, alpha = 0.05. NCT00462228 ↗
registry analysis (superiority or other test); Memantine vs Placebo; p = 1.00; Sign test; note: 12 week comparison, alpha = 0.05. NCT00462228 ↗
registry analysis (superiority or other test); Memantine vs Placebo; p = 0.34; Sign test; note: 6 week comparison, alpha = 0.05. NCT00462228 ↗
registry analysis (superiority or other test); Memantine vs Placebo; p = 0.54; Wilcoxon (Mann-Whitney); note: 6 week comparison, alpha = 0.05. NCT00462228 ↗
registry analysis (superiority or other test); Memantine vs Placebo; p = 0.91; Wilcoxon (Mann-Whitney); note: 12 week comparison, alpha = 0.05. NCT00462228 ↗
registry analysis (superiority or other test); Memantine vs Placebo; p = 0.55; Sign test; note: 12 week comparison, alpha = 0.05. NCT00462228 ↗
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Memantine | Unknown | 20 mg | — |