drugset / Trial / NCT00462956

GW572016 In Patients With Advanced Or Metastatic Breast Cancer

NCT00462956

Phase 1 Completed 59 enrolled GlaxoSmithKline
Non-randomizedSingle-groupOpen-labelTreatment

Summary

This study is designed to evaluate the efficacy and safety of GW572016 in patients with refractory breast cancer and consists of two cohorts of patients. Patients in Cohort A must have ErbB2 overexpressing tumors while patients in Cohort B must have non-ErbB2 overexpressing tumors. Patients eligible for this study must have advanced metastatic breast cancer who have previously received treatment with anthracycline and taxane.

Timeline

Start
2004-06-30
Primary completion
2006-12-20
Completion
2006-12-20

Drugs

EvaluationDrugModalityDoseRoute
Subject Lapatinib Small molecule 1500 mg Oral

Indications