Psychopharmacology of Psilocybin in Cancer Patients

Phase 2 Completed 56 enrolled Johns Hopkins University Heffter Research Institute · collab

RandomizedCrossoverQuadruple-blindSupportive care

Summary

This research is being done to study the psychological effects of psilocybin in cancer patients. Psilocybin is a naturally occurring substance found in some mushrooms that some cultures have used for centuries in religious practices.

Timeline

Start: 2007-04
Primary completion: 2014-12
Completion: 2016-12

Publications

Results Griffiths RR, Johnson MW, Carducci MA, Umbricht A, Richards WA, Richards BD, Cosimano MP, Klinedinst MA. Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial. J Psychopharmacol. 2016 Dec;30(12):1181-1197. doi: 10.1177/0269881116675513.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Psilocybin	Other / unclassified	0.0142857 mg/kg	—
Subject	Psilocybin	Other / unclassified	0.0428571 mg/kg	—
Subject	Psilocybin	Other / unclassified	0.314286 mg/kg	—
Subject	Psilocybin	Other / unclassified	0.428571 mg/kg	—

Psychopharmacology of Psilocybin in Cancer Patients

Summary

Timeline

Publications

Drugs

Indications