Effects of FXR Activation on Hepatic Lipid and Glucose Metabolism

Summary

The purpose of this study is to determine whether chenodeoxycholic acid decreases de novo hepatic lipogenesis, hepatic fat content, hepatic triglyceride production and plasma triglyceride concentrations and improves hepatic glucose metabolism in patients with the metabolic syndrome, Familial Hypertriglyceridemia and Familial Combined Hyperlipidemia.

Timeline

Start

2004-10

Primary completion

—

Completion

—

Drugs

Indications