drugset / Trial / NCT00465972
The Treatment of Insomnia in Patients With HIV Disease
RandomizedParallel-groupQuadruple-blindTreatment
Summary
This study is designed to evaluate the efficacy of two commonly prescribed sleep aids for use in patients who are HIV positive and suffer from insomnia.
Timeline
- Start
- 2007-03
- Primary completion
- 2010-08
- Completion
- 2010-08
Publications
- Background Reid S, Dwyer J. Insomnia in HIV infection: a systematic review of prevalence, correlates, and management. Psychosom Med. 2005 Mar-Apr;67(2):260-9. doi: 10.1097/01.psy.0000151771.46127.df.
- Low Y, Preud'homme X, Goforth HW, Omonuwa T, Krystal AD. The association of fatigue with depression and insomnia in HIV-seropositive patients: a pilot study. Sleep. 2011 Dec 1;34(12):1723-6. doi: 10.5665/sleep.1446.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Doxepin | Unknown | 10 mg | Oral |
| Comparator | Temazepam | Small molecule | 15 mg | Oral |