drugset / Trial / NCT00468234

Validation of Biomarkers of Exposure and Host Response

NCT00468234

Non-randomizedSingle-groupOpen-labelDiagnostic

Summary

This study will evaluate biomarkers measured in exhaled breath condensate (EBC) to assess clinical strategies of harm reduction. It will take advantage of a recently developed device that permits collection of exhaled breath condensate reproducibly, with minimal subject effort and with no oral contamination. Samples from asymptomatic smokers before and after inducing a change in their smoking habit (cessation or reduction) with the aid of partial nicotine replacement.

Timeline

Start
2005-12
Primary completion
2007-09
Completion
2007-09

Drugs

EvaluationDrugModalityDoseRoute
Background Nicotine Unknown

Indications

No indication recorded.