Assessment of the Effect of Sertaline on the Specific Binding of 123-I MZINT in Healthy Subjects

Summary

The overall purpose of this project is to evaluate the effect of sertraline administration on the binding of 123-I mZINT in 10 healthy subjects. All study procedures will be conducted at the Institute for Neurodegenerative Disorders (IND) and Molecular NeuroImaging (MNI) in New Haven, CT.

Timeline

Start

2007-05

Primary completion

2008-02

Completion

2008-02

Publications

• Background Brooks DJ, Piccini P. Imaging in Parkinson's disease: the role of monoamines in behavior. Biol Psychiatry. 2006 May 15;59(10):908-18. doi: 10.1016/j.biopsych.2005.12.017. Epub 2006 Apr 11.

Drugs

Indications