drugset / Trial / NCT00470990

Effect of Varying Testosterone Levels on Insulin Sensitivity in Normal and IHH Men

NCT00470990

CrossoverOpen-label

Summary

Type 2 diabetes is one of the most common metabolic disorders in the U.S, estimated to affect 16 million Americans. Established risk factors for this disease include obesity, increased waist/hip ratio, high insulin levels in the blood, and insulin resistance. Testosterone may play a role in developing or preventing diabetes, but we do not yet know for sure. The purpose of this research study is to determine if changing testosterone levels in men will result in changes in insulin sensitivity. Information learned form this research study may have important public health implications and may point to new strategies for treating or preventing diabetes.

Timeline

Start
2002-10
Primary completion
2008-06
Completion
2008-06

Drugs

EvaluationDrugModalityDoseRoute
Background Acyline Protein / enzyme biologic 300 ug/kg Subcutaneous

Indications