drugset / Trial / NCT00470990
Effect of Varying Testosterone Levels on Insulin Sensitivity in Normal and IHH Men
Completed
40 enrolled
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
American Diabetes Association · collab
CrossoverOpen-label
Summary
Type 2 diabetes is one of the most common metabolic disorders in the U.S, estimated to affect 16 million Americans. Established risk factors for this disease include obesity, increased waist/hip ratio, high insulin levels in the blood, and insulin resistance. Testosterone may play a role in developing or preventing diabetes, but we do not yet know for sure. The purpose of this research study is to determine if changing testosterone levels in men will result in changes in insulin sensitivity. Information learned form this research study may have important public health implications and may point to new strategies for treating or preventing diabetes.
Timeline
- Start
- 2002-10
- Primary completion
- 2008-06
- Completion
- 2008-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Background | Acyline | Protein / enzyme biologic | 300 ug/kg | Subcutaneous |