drugset

drugset / Trial / NCT00472355

Low Dose Apomorphine and Parkinsonism

NCT00472355 ↗

Phase 2 Withdrawn Oregon Health and Science University National Institute of Neurological Disorders and Stroke (NINDS) · collab

RandomizedCrossoverDouble-blindTreatment

Summary

The purpose of this study is to determine if low doses of apomorphine worsen the motor symptoms of Parkinson's disease.

Timeline

Start: 2005-10
Primary completion: 2007-05
Completion: 2007-05

Publications

Gunzler SA, Koudelka C, Carlson NE, Pavel M, Nutt JG. Effect of low concentrations of apomorphine on parkinsonism in a randomized, placebo-controlled, crossover study. Arch Neurol. 2008 Feb;65(2):193-8. doi: 10.1001/archneurol.2007.58.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Apomorphine	Unknown	12.5 ug/kg	Subcutaneous
Subject	Apomorphine	Unknown	25 ug/kg	Subcutaneous
Subject	Apomorphine	Unknown	50 ug/kg	Subcutaneous
Subject	Apomorphine	Unknown	100 ug/kg	Subcutaneous

Indications