drugset

drugset / Trial / NCT00476879

Growth Hormone During Fasting.Signaltransduktion in Muscle and Adipose Tissue and Changes in Intrahepatic Lipid Content

NCT00476879 ↗

Completed 10 enrolled University of Aarhus Aarhus University Hospital · collab Pfizer · collab

RandomizedParallel-groupOpen-labelBasic science

Summary

The purpose of this study is to examine the effects of growth hormone during fasting in healthy lean men.

Timeline

Start: 2006-08
Primary completion: 2007-11
Completion: 2008-06

Publications

Moller L, Norrelund H, Jessen N, Flyvbjerg A, Pedersen SB, Gaylinn BD, Liu J, Thorner MO, Moller N, Lunde Jorgensen JO. Impact of growth hormone receptor blockade on substrate metabolism during fasting in healthy subjects. J Clin Endocrinol Metab. 2009 Nov;94(11):4524-32. doi: 10.1210/jc.2009-0381. Epub 2009 Oct 9.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Pegvisomant	Protein / enzyme biologic	0.5 mg	Subcutaneous
Subject	Somatropin	Protein / enzyme biologic	—	Intravenous

Indications