drugset / Trial / NCT00478699
Randomized Customized Adjuvant Chemotherapy (GECP-SCAT)
RandomizedParallel-groupOpen-labelTreatment
Summary
Randomized Study of Customized Adjuvant Chemotherapy based on BRCA1 mRNA Levels in Completely Resected stages II-IIIA Non-Small-Cell Lung Cancer Patients.
Timeline
- Start
- 2007-06
- Primary completion
- 2015-06
- Completion
- 2015-07
Outcome
Missed primary endpoint
registry analysis (superiority test); Control Arm vs Experimental Arm; p = 0.73; Hazard Ratio (HR) 0.946 (95% CI 0.689 to 1.298); Log Rank NCT00478699 ↗
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Cisplatin | Other / unclassified | 75 mg/m2 | — |
| Subject | Docetaxel | Small molecule | 75 mg/m2 | — |
| Subject | Gemcitabine | Small molecule | 1250 mg/m2 | — |