drugset / Trial / NCT00479128

Bortezomib With Gemcitabine/Doxorubicin in Patients With Urothelial Cancer and Other Solid Tumors

NCT00479128 ↗

Phase 1 Active not recruiting 80 enrolled M.D. Anderson Cancer Center
NaSingle-groupOpen-labelTreatment

Summary

The goal of this clinical research study is to find the highest tolerable dose of Gemzar® (gemcitabine) and Adriamycin® (doxorubicin) that can be given together with Velcade® (bortezomib) in patients with urothelial cancer or other solid tumors.

Timeline

Start
2006-09-28
Primary completion
2026-09-30
Completion
2026-09-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Bortezomib Small molecule 0.8 mg/m2 Intravenous
Subject Doxorubicin Other / unclassified 12.5 mg/m2 Intravenous
Subject Gemcitabine Small molecule 225 mg/m2 Intravenous

Indications