drugset / Trial / NCT00480272
Prospective Study on Intensive Early Rheumatoid Arthritis Treatment
RandomizedParallel-groupQuadruple-blindTreatment
Summary
Hypothesis: Early intensive treatment with anti-TNF agent plus methotrexate plus high dose prednisone may increase remission rate and may induce stable remission in Rheumatoid Arthritis Objective: to evaluate induction of remission using adalimumab, prednisone and methotrexate and maintenance of remission after discontinuation of adalimumab and prednisone
Timeline
- Start
- 2007-05
- Primary completion
- 2017-03-01
- Completion
- 2017-03-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Adalimumab | Monoclonal antibody | 40 mg | Subcutaneous |
| Subject | Prednisone | Other / unclassified | 6.25 mg | Oral |
| Background | Methotrexate | Small molecule | 20 mg | Oral |