24-hour Intraocular Pressure (IOP) Control With the Bimatoprost/Timolol Fixed Combination

Summary

The objective of this crossover, randomized, placebo controlled, double-masked study is to compare the short-term (12 weeks) mean 24-hour IOP control and safety of the new fixed combination (bimatoprost/timolol, BTFC) given PM with placebo once in the morning, versus BTFC given AM with placebo once in the evening versus bimatoprost given in the evening in patients with exfoliative glaucoma (XFG).

Timeline

Start

2007-03

Primary completion

2008-05

Completion

2008-07

Publications

• Konstas AG, Hollo G, Mikropoulos D, Tsironi S, Haidich AB, Embeslidis T, Georgiadou I, Irkec M, Melamed S. Twenty-four-hour intraocular pressure control with bimatoprost and the bimatoprost/timolol fixed combination administered in the morning, or evening in exfoliative glaucoma. Br J Ophthalmol. 2010 Feb;94(2):209-13. doi: 10.1136/bjo.2008.155317. Epub 2009 Oct 12.

Drugs

Indications