drugset / Trial / NCT00487058

A Phase I Dose Escalation Study of LBQ707 (Gimatecan) Administered Orally Twice Per Week to Japanese Patients With Advanced Solid Tumors

NCT00487058

Phase 1 Completed 28 enrolled Novartis
Non-randomizedSingle-groupOpen-labelTreatment

Summary

This study assesses the tolerability, safety, efficacy and pharmacokinetics of gimatecan in Japanese patients. Gimatecan is administered orally twice per week, every 28 days, to adult patients with advanced solid tumors who have progressed despite standard therapy or for whom standard systemic therapy dose not exist.

Timeline

Start
2007-05
Primary completion
2008-06
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Gimatecan Small molecule Oral

Indications