drugset / Trial / NCT00488605
H-9926-LCH III: Treatment Protocol of the Third International Study for Langerhans Cell Histiocytosis
RandomizedSingle-groupOpen-labelTreatment
Summary
LCH III is an international, multicentric, prospective clinical study comprised of: * a randomized clinical trial for multisystem "RISK" patients and * a randomized clinical trial for multisystem "LOW RISK" patients and * a pilot study for patients with single system MFB and localized "SPECIAL SITES"
Timeline
- Start
- 2023-08-01
- Primary completion
- 2023-08-01
- Completion
- 2023-08-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | 6-mercaptopuroine | Unknown | — | Oral |
| Subject | Methotrexate | Small molecule | — | Intravenous |
| Background | Leucovorin | Small molecule | — | Oral |
| Comparator | Prednisone | Other / unclassified | — | Oral |
| Comparator | Vinblastine | Small molecule | — | Intravenous |