drugset / Trial / NCT00490191

Comparison of Two Growth Hormone Dosing Methods in Adults With Growth Hormone Deficiency

NCT00490191

Phase 4 Completed 387 enrolled Eli Lilly and Company
RandomizedParallel-groupOpen-labelTreatment

Summary

This study tested whether a dose regimen of growth hormone based on body weight is equivalent or better than starting with a low dose and gradually increasing the dose according to individual patient needs. Efficacy of the two regimens were assessed from changes in body fat measured by dual-energy x-ray absorptiometry (DXA) scanning, performed at the beginning of the study and at the completion of the study eight months later.

Timeline

Start
1999-01
Primary completion
Completion
2001-07

Drugs

EvaluationDrugModalityDoseRoute
Subject Somatropin Protein / enzyme biologic 12 ug/kg
Subject Somatropin Protein / enzyme biologic 800 ug

Indications