drugset / Trial / NCT00490191
Comparison of Two Growth Hormone Dosing Methods in Adults With Growth Hormone Deficiency
RandomizedParallel-groupOpen-labelTreatment
Summary
This study tested whether a dose regimen of growth hormone based on body weight is equivalent or better than starting with a low dose and gradually increasing the dose according to individual patient needs. Efficacy of the two regimens were assessed from changes in body fat measured by dual-energy x-ray absorptiometry (DXA) scanning, performed at the beginning of the study and at the completion of the study eight months later.
Timeline
- Start
- 1999-01
- Primary completion
- —
- Completion
- 2001-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Somatropin | Protein / enzyme biologic | 12 ug/kg | — |
| Subject | Somatropin | Protein / enzyme biologic | 800 ug | — |