drugset / Trial / NCT00492141
Aerosol L9-NC and Temozolomide in Ewing's Sarcoma
Non-randomizedSingle-groupOpen-labelTreatment
Summary
Primary Objectives: 1. To determine the feasibility and toxicity profile of administering liposomal 9-Nitro-20-(S)-Camptothecin (L9-NC) by aerosol alone and in combination with temozolomide. 2. To determine the effectiveness of L9-NC given by aerosol in combination with temozolomide in patients with solid tumors involving the lungs.
Timeline
- Start
- 2006-06
- Primary completion
- 2007-05
- Completion
- 2009-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Temozolomide | Small molecule | 100 mg/m2 | Oral |
| Subject | rubitecan | Unknown | 0.4 mg/ml | Inhaled |