drugset / Trial / NCT00493441

AVN944 in Combination With Gemcitabine for the Treatment of Pancreatic Cancer

NCT00493441 ↗

Phase 2 Terminated 28 enrolled Vertex Pharmaceuticals Incorporated
Non-randomizedSingle-groupOpen-labelTreatment

Summary

The study was designed to find the optimum AVN944 dose to use in combination with gemcitabine in patients with pancreatic cancer and see if the combination of the 2 drugs was more effective for treating pancreatic cancer than using gemcitabine alone.

Timeline

Start
2007-06
Primary completion
2009-12
Completion
2009-12

Drugs

EvaluationDrugModalityDoseRoute
Subject AVN944 Small molecule 150 mg —
Subject AVN944 Small molecule 200 mg —
Subject AVN944 Small molecule 250 mg —
Subject AVN944 Small molecule 300 mg —
Subject AVN944 Small molecule 400 mg —