drugset / Trial / NCT00495586
Effectiveness of Antibiotic Therapy for Exacerbations of Chronic Obstructive Pulmonary Disease
Phase 4
Completed
318 enrolled
Societat Catalana de Medicina Familiar i Comunitària, Assoc. (CAMFiC)
Fondo de Investigacion Sanitaria · collab
RandomizedParallel-groupDouble-blindTreatment
Summary
The purpose of this study is to determine the effectiveness of antibiotic therapy for patients with acute exacerbations of mild-to-moderate chronic obstructive pulmonary disease.
Timeline
- Start
- 2007-10
- Primary completion
- 2010-07
- Completion
- 2011-07
Publications
- Miravitlles M, Moragas A, Hernandez S, Bayona C, Llor C. Is it possible to identify exacerbations of mild to moderate COPD that do not require antibiotic treatment? Chest. 2013 Nov;144(5):1571-1577. doi: 10.1378/chest.13-0518.
- Llor C, Moragas A, Hernandez S, Bayona C, Miravitlles M. Efficacy of antibiotic therapy for acute exacerbations of mild to moderate chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2012 Oct 15;186(8):716-23. doi: 10.1164/rccm.201206-0996OC. Epub 2012 Aug 23.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Amoxicillin | Other / unclassified | 500 mg | — |
| Comparator | clavulanic acid | Small molecule | 125 mg | — |