drugset / Trial / NCT00496808

Neoadjuvant Herceptin for Ductal Carcinoma In Situ of the Breast

NCT00496808

Completed 69 enrolled M.D. Anderson Cancer Center
NaSingle-groupOpen-labelTreatment

Summary

Primary Objectives: * To determine the effect of a single dose of Herceptin (trastuzumab) on the proliferation rate of Her-2/neu over-expressing ductal carcinoma in situ (DCIS) * To evaluate the effect of a single dose of Herceptin on the apoptotic index of Her-2/neu over-expressing DCIS

Timeline

Start
2005-03
Primary completion
2010-11
Completion
2010-11

Drugs

EvaluationDrugModalityDoseRoute
Subject Trastuzumab Monoclonal antibody 8 mg/kg Intravenous