drugset / Trial / NCT00499460

Effects of Garlic Supplements on Opioids in Healthy Volunteers

NCT00499460

RandomizedCrossoverSingle-blindBasic science

Summary

RATIONALE: Garlic supplements may alter the pharmacokinetics of oxycodone, thereby affecting its effectiveness as an opioid analgesic for the relief of moderate or severe pain. PURPOSE: This randomized phase 4 trial is studying how garlic supplements may change the pharmacokinetics of oxycodone and its analgesic and side effects in healthy volunteers.

Timeline

Start
2006-11
Primary completion
2008-08
Completion
2008-08

Drugs

EvaluationDrugModalityDoseRoute
Subject Oxycodone Other / unclassified 15 mg Oral

Indications

No indication recorded.