CAPTAIN:Choroidal Neovascularization Assessment by Pattern Electroretinography

Summary

CNV from AMD is the leading cause of blindness in people over 50 in North America. The hypothesis is to determine if there is an improvement in retinal function determined by ERG following treatment with ranibizumab for AMD

Timeline

Start

2007-07

Primary completion

2009-03

Completion

2009-03

Publications

• Background Klein R, Peto T, Bird A, Vannewkirk MR. The epidemiology of age-related macular degeneration. Am J Ophthalmol. 2004 Mar;137(3):486-95. doi: 10.1016/j.ajo.2003.11.069.
• Background van Leeuwen R, Klaver CC, Vingerling JR, Hofman A, de Jong PT. Epidemiology of age-related maculopathy: a review. Eur J Epidemiol. 2003;18(9):845-54. doi: 10.1023/a:1025643303914.
• Sheybani A, Brantley MA Jr, Apte RS. Pattern electroretinography in age-related macular degeneration. Arch Ophthalmol. 2011 May;129(5):580-4. doi: 10.1001/archophthalmol.2011.83.

Drugs

Indications