drugset / Trial / NCT00500461

Study To Examine Safety, Tolerability And Pharmacokinetics Of Intravenous Doses And Oral Dose Of GSK233705

NCT00500461

Phase 1 Completed 9 enrolled GlaxoSmithKline
Non-randomizedCrossoverOpen-labelTreatment

Summary

GSK233705 is being developed for the treatment of chronic obstructive pulmonary disease. This will be an open-label, dose-ascending study in 7 healthy male subjects to establish well tolerated intravenous doses and an oral dose of GSK233705. The main objective of the study is to confirm an IV and oral dose for a definitive human radiolabel metabolic study.

Timeline

Start
2007-06-04
Primary completion
2007-07-01
Completion
2007-07-25

Publications

  • Background This study has not been published in the scientific literature.

Drugs

EvaluationDrugModalityDoseRoute
Subject DAROTROPIUM Small molecule 10 ug Intravenous
Subject DAROTROPIUM Small molecule 30 ug Intravenous
Subject DAROTROPIUM Small molecule 70 ug Intravenous
Subject DAROTROPIUM Small molecule 110 ug Intravenous
Subject DAROTROPIUM Small molecule 250 ug Intravenous