drugset / Trial / NCT00500461
Study To Examine Safety, Tolerability And Pharmacokinetics Of Intravenous Doses And Oral Dose Of GSK233705
Non-randomizedCrossoverOpen-labelTreatment
Summary
GSK233705 is being developed for the treatment of chronic obstructive pulmonary disease. This will be an open-label, dose-ascending study in 7 healthy male subjects to establish well tolerated intravenous doses and an oral dose of GSK233705. The main objective of the study is to confirm an IV and oral dose for a definitive human radiolabel metabolic study.
Timeline
- Start
- 2007-06-04
- Primary completion
- 2007-07-01
- Completion
- 2007-07-25
Publications
- Background This study has not been published in the scientific literature.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | DAROTROPIUM | Small molecule | 10 ug | Intravenous |
| Subject | DAROTROPIUM | Small molecule | 30 ug | Intravenous |
| Subject | DAROTROPIUM | Small molecule | 70 ug | Intravenous |
| Subject | DAROTROPIUM | Small molecule | 110 ug | Intravenous |
| Subject | DAROTROPIUM | Small molecule | 250 ug | Intravenous |