drugset / Trial / NCT00503828

Derris Scandens Benth Extract VS Naproxen in Knee OA

NCT00503828

RandomizedParallel-groupSingle-blindTreatment

Summary

Derris Scandens Benth (family : Leguminosae) is a woody vine growing throughout Southeast Asia, including Thailand. The stem of D.Scandens has been widely use in Thai traditional medicine, foe example of myalgia. Previous study shown that D.Scandens Benth extract has the anti-inflammatory activity. Although NSAIDs are efficaciously in the treatment of osteoarthritis,but the GI side effect is still concerned. In this study we aim to investigate the efficacy and safety of D. Scandens Benth extract compared with Naproxen for therapy of patients with knee osteoarthritis.

Timeline

Start
2007-07
Primary completion
2009-03
Completion
2009-03

Drugs

EvaluationDrugModalityDoseRoute
Subject Derris Scandens Benth Traditional medicine (herbal / TCM) 400 mg Oral
Comparator Naproxen Small molecule 500 mg

Indications