Enhancing Slow Wave Sleep With Sodium Oxybate

Phase 4 Completed 60 enrolled St. Luke's Hospital, Chesterfield, Missouri Jazz Pharmaceuticals · collab

RandomizedParallel-groupDouble-blindBasic science

Summary

The purpose of this study is to determine if there the impact of sleep deprivation upon sleepiness, attention, memory, and mood is reduced by pharmacologically enhancing slow wave sleep (SWS) with sodium oxybate.

Timeline

Start: 2007-05
Primary completion: 2008-06
Completion: 2008-06

Publications

Background Walsh JK, Hartman PG, Schweitzer PK. Slow-wave sleep deprivation and waking function. J Sleep Res. 1994 Mar;3(1):16-25. doi: 10.1111/j.1365-2869.1994.tb00099.x.
Background Walsh JK, Randazzo AC, Stone K, Eisenstein R, Feren SD, Kajy S, Dickey P, Roehrs T, Roth T, Schweitzer PK. Tiagabine is associated with sustained attention during sleep restriction: evidence for the value of slow-wave sleep enhancement? Sleep. 2006 Apr;29(4):433-43.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Sodium Oxybate	Unknown	3.5 g	—

Indications

No indication recorded.