drugset / Trial / NCT00506987

Study of the Efficacy and Safety of SCH 486757 in Subjects With Chronic Cough (Study P04887)

NCT00506987 ↗

Phase 2 Completed 31 enrolled Merck Sharp & Dohme LLC
RandomizedCrossoverDouble-blindTreatment

Summary

This is a randomized, double-blind, placebo-controlled, crossover, single center study of SCH 486757 in subjects with chronic cough. Subjects will be randomized to receive SCH 486757 or placebo for 14 days. After a 2-week washout period, subjects will be crossed over to the other treatment. The primary objective is to evaluate the effectiveness of SCH 486757 in reducing cough reflex sensitivity as determined by a challenge with capsaicin, an agent that induces cough.

Timeline

Start
2007-01
Primary completion
2007-11
Completion
2007-11

Drugs

EvaluationDrugModalityDoseRoute
Subject SCH 486757 Small molecule 100 mg Oral

Indications

No indication recorded.