drugset / Trial / NCT00511524

An Imaging Study to Investigate the Distribution of GW842166X in the Brain.

NCT00511524 ↗

Phase 1 Completed 6 enrolled GlaxoSmithKline
Non-randomizedSingle-groupOpen-labelTreatment

Summary

GW842166X is being developed for the treatment and management of inflammatory pain. GW842166X is a CB2 receptor agonist and the mechanism is not fully understood, although it is thought that for the anti-inflammatory action the drug is required to cross inot the brain from the blood. This study aims to look at if the drug crosses into the brain once given orally using an imaging technique called positron emission tomography.

Timeline

Start
2007-06-26
Primary completion
2007-07-04
Completion
2007-07-04

Drugs

EvaluationDrugModalityDoseRoute
Subject GW842166X Small molecule 400 mg Oral
Subject [carbonyl-^11C]GW842166 Unknown — Intravenous

Indications