Omega-3 Fatty Acids as Adjunct Treatment for Major Depressive Disorder

Summary

The primary objective of the study was to determine the effects of 10-week adjunctive supplementation with 2 doses of LCn-3 fatty acids (fish oil) on cortical functional activity and biochemistry in adolescents with MDD. The primary prediction was that LCn-3 fatty acid supplementation would dose-dependently increase prefrontal cortical functional activation during sustained attention and increase regional biochemical indices of cortical metabolism and integrity concentrations in association with reductions in depressive symptoms.

Timeline

Start

2007-08

Primary completion

2011-03

Completion

2011-03

Drugs

Indications