drugset / Trial / NCT00514397

Temozolomide and Radiation Therapy in Treating Young Patients With Pontine Glioma

NCT00514397

Phase 2 Unknown 43 enrolled Children's Cancer and Leukaemia Group
Non-randomizedTreatment

Summary

RATIONALE: Drugs used in chemotherapy, such as temozolomide, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Radiation therapy uses high-energy x-rays to kill tumor cells. Giving temozolomide together with radiation therapy may kill more tumor cells. PURPOSE: This phase II trial is studying how well giving temozolomide together with radiation therapy works in treating young patients with pontine glioma.

Timeline

Start
2008-01
Primary completion
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Temozolomide Small molecule Oral
Background motexafin gadolinium Diagnostic / imaging agent