drugset / Trial / NCT00515268
Endotoxin Challenge Study For Healthy Men and Women
RandomizedParallel-groupDiagnostic
Summary
The proposed study will examine the effect of pre-treatment with inhaled GSK256066 using a lung inflammation model induced by bronchoscopic instillation of bacterial endotoxin (lipopolysaccharide, LPS) in healthy volunteers.Data from this study will be used to support GSK256066 dose selection for future studies in COPD patients.
Timeline
- Start
- 2007-09-27
- Primary completion
- 2008-04-23
- Completion
- 2008-04-23
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | GSK256066 | Small molecule | 25 ug | Inhaled |
| Subject | GSK256066 | Small molecule | 87.5 ug | Inhaled |