drugset / Trial / NCT00516919
Study of Behavioral Weight Loss Therapy for Obesity and Binge Eating in Monolingual Hispanic Persons
RandomizedParallel-groupQuadruple-blindTreatment
Summary
This is a research study designed to examine the effectiveness of an obesity medication (orlistat) given in addition to behavioral weight loss therapy. Participants will be obese monolingual (Spanish-speaking only) men and women.
Timeline
- Start
- 2007-08
- Primary completion
- 2010-12
- Completion
- 2010-12
Outcome
Missed primary endpoint
registry analysis (unspecified test); Drug: Xenical + Behavioral: Behavioral Intervention vs Drug: Placebo + Behavioral: Behavioral Intervention; p =0.51; F statistic 0.45; ANCOVA NCT00516919 ↗
registry analysis (unspecified test); Drug: Xenical + Behavioral: Behavioral Intervention vs Drug: Placebo + Behavioral: Behavioral Intervention; p =0.41; F statistic 0.69; ANCOVA NCT00516919 ↗
Publications
- Grilo CM, Kerrigan SG, Lydecker JA, White MA. Physical activity changes during behavioral weight loss treatment by Latinx patients with obesity with and without binge eating disorder. Obesity (Silver Spring). 2021 Dec;29(12):2026-2034. doi: 10.1002/oby.23278. Epub 2021 Sep 28.
- Grilo CM, White MA. Orlistat with behavioral weight loss for obesity with versus without binge eating disorder: randomized placebo-controlled trial at a community mental health center serving educationally and economically disadvantaged Latino/as. Behav Res Ther. 2013 Mar;51(3):167-75. doi: 10.1016/j.brat.2013.01.002. Epub 2013 Jan 18.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Orlistat | Small molecule | 120 mg | — |