drugset / Trial / NCT00523068

Pharmacological vs Surgical Treatment for Mixed Incontinence

NCT00523068

Phase 4 Withdrawn Imperial College London
RandomizedParallel-groupOpen-labelTreatment

Summary

In patients with symptoms of mixed incontinence (loss of urine associated with coughing/sneezing/laughing, and loss of urine associated with the strong urge to void), is surgical treatment with tension free vaginal tape or pharmacological treatment with tolterodine more effective? What are the parameters predictive of success or failure with either forms of treatment? What are the parameters predictive of the necessity for further treatment after primary treatment? Patients will be randomised to having surgical or pharmacological treatment for their mixed incontinence symptoms. They will be assessed subjectively and objectively pre-treatment and after treatment at intervals up to 3 months.

Timeline

Start
2007-09
Primary completion
2010-01
Completion
2010-01

Drugs

EvaluationDrugModalityDoseRoute
Comparator Tolterodine Small molecule 4 mg