drugset / Trial / NCT00524316

Sunitinib and Chemoembolization in Treating Patients With Liver Cancer That Cannot Be Removed by Surgery

NCT00524316 ↗

Phase 2 Terminated 16 enrolled Roswell Park Cancer Institute
NaSingle-groupOpen-labelTreatment

Summary

RATIONALE: Sunitinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor. Chemoembolization kills tumor cells by blocking the blood flow to the tumor and keeping chemotherapy drugs, such as doxorubicin, near the tumor. Giving sunitinib together with chemoembolization may kill more tumor cells. PURPOSE: This phase II trial is studying how well giving sunitinib together with chemoembolization works in treating patients with liver cancer that cannot be removed by surgery.

Timeline

Start
2007-04
Primary completion
2010-12
Completion
2014-05

Outcome

Outcome not reported

Stopped (Enrollment): “low accrual”

Drugs

EvaluationDrugModalityDoseRoute
Subject Sunitinib Small molecule — Oral
Background Doxorubicin Other / unclassified — Other

Indications