drugset / Trial / NCT00525772
Effect of Ciclesonide on Exercise Induced Bronchoconstriction
Phase 3
Completed
26 enrolled
Hamilton Health Sciences Corporation
Kolding Sygehus · collabTakeda · collab
RandomizedCrossoverQuadruple-blindTreatment
Summary
The purpose of this study is to study the effects of once daily inhaled ciclesonide at varying doses on exercise provoked asthma symptoms, fall in lung function after exercise and sputum characteristics.
Timeline
- Start
- 2001-11
- Primary completion
- 2007-11
- Completion
- 2007-11
Publications
- Background Subbarao P, Duong M, Adelroth E, Otis J, Obminski G, Inman M, Pedersen S, O'byrne PM. Effect of ciclesonide dose and duration of therapy on exercise-induced bronchoconstriction in patients with asthma. J Allergy Clin Immunol. 2006 May;117(5):1008-13. doi: 10.1016/j.jaci.2005.11.048.
- Duong M, Subbarao P, Adelroth E, Obminski G, Strinich T, Inman M, Pedersen S, O'Byrne PM. Sputum eosinophils and the response of exercise-induced bronchoconstriction to corticosteroid in asthma. Chest. 2008 Feb;133(2):404-11. doi: 10.1378/chest.07-2048. Epub 2007 Dec 10.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Ciclesonide | Other / unclassified | 50 ug | Inhaled |
| Comparator | Ciclesonide | Other / unclassified | 100 ug | Inhaled |
| Comparator | Ciclesonide | Other / unclassified | 200 ug | Inhaled |
| Comparator | Ciclesonide | Other / unclassified | 400 ug | Inhaled |