drugset / Trial / NCT00526006
PPI-Rebound-Trial. A Study of the Clinical Relevance of the Acid Rebound Phenomena
RandomizedParallel-groupQuadruple-blindTreatment
Summary
The acid secretion in the stomach seems to increase after withdrawal of min. 8 wks of treatment with a PPI (protonpump inhibitor) It is unknown if this acid rebound phenomenon is of clinical significance. In a doubleblinded and placebocontrolled study healthy volunteers are randomized to treatment with placebo or PPI + placebo. Gastrointestinal symptoms are scored once a week and.
Timeline
- Start
- 2007-09
- Primary completion
- —
- Completion
- 2008-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Esomeprazole | Small molecule | 40 mg | — |
Indications
No indication recorded.