drugset / Trial / NCT00526838

Study of XL228 Administered Intravenously to Subjects With Advanced Malignancies

NCT00526838 ↗

Phase 1 Terminated 84 enrolled Exelixis
Non-randomizedSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to assess the safety and tolerability of the multi-targeted protein kinase inhibitor XL228 (active against IGF1R, Src, FGFR, and BCR-Abl) administered as a once- or twice-weekly 1-hour intravenous infusion in subjects with advanced malignancies.

Timeline

Start
2007-09
Primary completion
2010-12
Completion
2010-12

Outcome

Outcome not reported

Stopped (Business): “Sponsor decision”

Drugs

EvaluationDrugModalityDoseRoute
Subject XL228 Small molecule — Intravenous

Indications