Safety and Efficacy of Ferriprox™ (Deferiprone) Oral Solution in Iron Overloaded Pediatric Patients

Phase 3 Completed 100 enrolled ApoPharma

Non-randomizedSingle-groupOpen-labelTreatment

Summary

* The primary objective is to assess the safety of Ferriprox oral solution for the treatment of iron overload in pediatric patients with transfusion-dependent anemia. * The secondary objective is to assess the efficacy of Ferriprox oral solution in reducing iron overload in pediatric patients with transfusion-dependent anemia.

Timeline

Start: 2007-08
Primary completion: 2008-07
Completion: 2008-07

Publications

ElAlfy MS, Sari TT, Lee CL, Tricta F, El-Beshlawy A. The safety, tolerability, and efficacy of a liquid formulation of deferiprone in young children with transfusional iron overload. J Pediatr Hematol Oncol. 2010 Nov;32(8):601-5. doi: 10.1097/MPH.0b013e3181ec0f13.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Deferiprone	Small molecule	75 mg/kg	Oral
Subject	Deferiprone	Small molecule	100 mg/kg	Oral

Safety and Efficacy of Ferriprox™ (Deferiprone) Oral Solution in Iron Overloaded Pediatric Patients

Summary

Timeline

Publications

Drugs

Indications