drugset / Trial / NCT00529555
Periocline as an Adjunct to Scaling and Root Planing for Adult Periodontitis
RandomizedParallel-groupTriple-blindTreatment
Summary
Periodontal disease (commonly called gum disease) is generally treated by deep cleaning of the root surfaces of the teeth. This is also called scaling and root planing. Placing a topical antibiotic into the periodontal pocket at the time of scaling and root planing may help reduce pocket depth and thus help the periodontal disease. Periocline (minocycline HCl) 2.1% gel is a topical antibiotic approved in a number of countries for this use, and is now being tested in the US.
Timeline
- Start
- 2006-01
- Primary completion
- 2008-12
- Completion
- 2008-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Minocycline | Small molecule | 2.1 % | Topical |