drugset / Trial / NCT00534625
Assessment of PFT, Safety, and PK of Zileuton Injection in Asthma Patients
RandomizedCrossoverQuadruple-blindTreatment
Summary
A single intravenous injection of zileuton (150 or 300 mg) will be administered to patients with stable asthma. The goals will be to determine if zileuton i.v. can produce a rapid increase in FEV1/PEFR and when this effect can be seen. The safety of this route of administration of zileuton will also be studied. PK will be obtained in a population based method.
Timeline
- Start
- 2007-09
- Primary completion
- 2008-03
- Completion
- 2008-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Zileuton | Small molecule | 150 mg | Intravenous |
| Subject | Zileuton | Small molecule | 300 mg | Intravenous |